Dr. Xiaoming Jie

Prof. Antonio M. Echavarren

Dinuclear Gold Catalysis: A New Platform for Cross-Coupling Reactions

ICIQ profile

From 01/01/2019 to



Gold catalysis has become a powerful tool for organic chemists to streamline synthesis of valuable and complex molecules.
Compared to other transition metals, gold complexes are remarkably stable towards air and water, and are essentially nontoxic, which make them ideal candidates to execute catalytic cross-coupling reactions in industry or in vivo. TWINGOLD
aims at broadening the current applications of gold catalysis, exploring and identifying reliable dinuclear gold(I) catalysts in
C-C forming reactions. The use of dinuclear gold catalysts could lower activation barriers of chemical transformations and
thus allow access to reaction pathways that are difficult to accomplish with mononuclear gold systems. TWINGOLD will
promote gold catalysis significantly by exploring novel cross-coupling reactions and the related mechanistic elements behind
them, enabling use of more diverse raw materials and, thus, ensuring a more sustainable and inclusive economy in EU. In
addition, the project will enable the Experienced Researcher to develop a full range of scientific and transferable skills
following a personalized Career Development Plan to become an established researcher (R3).

This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement 792649